Hyperbaric Oxygen Therapy History & Research

As early as the 1800s, a Bulletin of the Academe of Medicine reported on the wonderful recovery achieved in patients from a variety of debilitating conditions - all through the use of oxygen.

Please call us on 01458 860 425 or email info@originoxygen.co.uk to hire an oxygen chamber, for more information or some hyperbaric oxygen therapy advice.

Hyperbaric therapy research Somerset

The effects of compressed oxygen were further studied and developed in the early 1900s by John Scott Haldane, who became known as the 'father of decompression'.

Haldane studied the beneficial effects of hyperbaric oxygen therapy on decompression sickness (the 'bends') in divers and subsequently created diving tables giving decompression times for staged return to the surface from deep water.

In 1928, Harvard Medical School had a hyperbaric oxygen chamber built. It provided a tool for years of research into its therapeutic benefits.

Public interest for HBOT started to grow in the 1960s, after publicity about its use to benefit President Kennedy's sickly infant. It has long been used for emergency recovery in hospitals and in recent years its benefits have been rediscovered for a wide range of health issues and wellbeing.

HBOT for Wound Healing

In a University of Amsterdam review of studies on the use of HBOT for difficult to heal acute wounds, the scientists confirmed that HBOT was effective for the management of these wounds. The studies showed that with HBOT, more crush wounds healed well, there were significantly fewer additional surgical procedures required and significantly less tissue necrosis. Burn wounds healed significantly quicker with HBOT than with routine burn care and skin graft outcomes were improved.

https://pubmed.ncbi.nlm.nih.gov/16604253/

A scientific review published in Wound Care and Rehab Medicine concluded that there is a high level of evidence that HBOT reduces the risk of limb amputation by promoting healing of problem wounds. Also that HBOT puts lower extremity osteomyelitis (bone infection) into remission.

https://pubmed.ncbi.nlm.nih.gov/19627935/

A study published in the Journal of the Missouri Medical Association concluded that HBOT can improve healing of necrotizing infections or crush injuries and promote healing and recovery for a variety of problems from radiation injury to the ravages of diabetes, as well as being effective for severe anaemia and as an alternative to a blood transfusion.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690302/

HBOT for Pain Relief

A study at the Gulhane Military Medical Academy, Turkey concluded that HBOT is an effective method of decreasing pain and oedema and increasing the range of motion in Complex Regional Pain Syndrome. The symptoms of CRPS arise from the sensory, motor and sympathetic nervous systems.

https://connect.hyperbaricmedicalsolutions.com/hubfs/HyperbaricMedicalSolutions_July2018/Docs/HBOT-in-CRPS.pdf

A group of US scientists at various universities and air force facilities found a significant decrease in pain from Rheumatoid Arthritis when HBOT is used and concluded that Hyperbaric oxygen therapy is effective for joint pain in patients with RA based on data from multiple, validated clinical measures.

https://pubmed.ncbi.nlm.nih.gov/32947434/

Bone Health

A study published in the Journal of Bone and Mineral Metabolism examined the effects of HBOT on osteoporosis and concluded that HBOT both inhibited bone loss and enhanced bone formation.

https://link.springer.com/article/10.1007/s00774-020-01100-6

A study from the International Journal of Molecular sciences stated that HBOT could have a promising future as an adjunctive therapeutic approach for treating the many challenges of cases of inflammation-related bone loss.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073059/

In a Brazilian study on diabetic rats, HBOT was shown to be an important treatment for minimizing the deleterious effects of diabetes on bone health and regeneration.

https://pubmed.ncbi.nlm.nih.gov/29378458/

A Brazilian study concluded that exposure to HBOT enhances bone anabolism (constructive metabolism), reduces inflammation and accelerates bone healing in rats within seven days.

https://pubmed.ncbi.nlm.nih.gov/26324750/

Physiotherapist Brian G. Simpson M.C.S.P.,DSA(CSP) is a highly experienced specialist in fracture healing, especially with professional motor cycle and racing car riders after accidents. Based on his in-depth studies and practical experience, he demonstrates in an important research paper that fractures can be influenced by various modalities to heal faster than conventionally considered possible.

This can help those who suffer from a fracture to benefit from movement much more quickly. They are also able to reduce healing time, experience less pain and return to work faster.

Brian Simpson and Matthew Jackson of Origin Oxygen - HBOT chambers to rent or buy

Matthew Jackson of Origin Oxygen and Brian Simpson

The paper covers:
In-depth study of the nature of bones and how they heal.
How the period of non-weight bearing and immobilisation can be reduced, often leading to better healing and stronger bones.

How surgical intervention can be avoided in the case of delayed or non-union fractures.
Healing modalities examined include Hyperbaric oxygen therapy, PEMF and laser therapy, all of which we offer as a one-stop combined treatment.

Brian Simpson is now sharing his knowledge and experience with us at Somerset Health Clinic:
The structure and physiology of bone and physiotherapeutic modalities to promote fracture healing. Brian G. Simpson M.C.S.P.,DSA(CSP) (pdf)

Cancer

A study at the University of Bergen, Norway, examined the effect of HBOT on tumour growth and other factors in mice with breast cancer. It concluded that HBOT had a suppressive effect on tumour growth. Furthermore, HBOT significantly reduced the number and area of metastatic lesions and reduced cancer markers, all of which would make chemotherapy more effective.

https://pubmed.ncbi.nlm.nih.gov/28832662/

Covid-19 Related

Given the high mortality rate and use of mechanical ventilation for Covid-19 patients with severe breathing difficulties, a study at hospitals and university schools of medicine in New York State evaluated the safety and efficacy of hyperbaric oxygen for Covid-19 patients with respiratory distress. The results were positive and the scientists and doctors strongly recommended a wider trial.

https://pubmed.ncbi.nlm.nih.gov/32931666/

Inflammatory bowel disease

Research conducted at the Rossignol Medical Centre, Melbourne, Australia reviewed studies of HBOT for Crohn's disease and ulcerative colitis which had become resistant to corticosteroids, immune modulators and anti-inflammatory medications. It found that HBOT improved the conditions of 78% of patients with Crohn's and all patients with ulcerative colitis. It also lowered markers for inflammation and oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328239/

Injuries

In a study published in Therapeutic Advances in Musculoskeletal Disease, the authors noted the increasing need for treatments that allow injured athletes to return to competition faster with a low risk of re-injury. They also note that oxygen is vital for healing the three phases of injury - inflammatory, proliferative and remodelling. They considered that HBOT has best effect for muscle-tendon junctions and ligaments and recommended larger trials to determine optimal frequency and length of treatment in the HBOT chamber.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382683/

A study published in the Journal of the Undersea and Hyperbaric Medical Society concluded that HBOT increased cell growth and that its action could result in mechanically stronger collagen fibrils. It proposed HBO2 therapy as a potentially effective treatment for healing medial collateral ligament injuries.

https://pubmed.ncbi.nlm.nih.gov/17672174/

Fibromyalgia / ME / Chronic Fatigue

A study by doctors and research scientists in Israel concluded that HBOT can improve the symptoms and life quality of patients with Fibromyalgia syndrome. They also showed that HBOT can induce neuroplasticity and significantly rectify abnormal brain activity in pain related areas of FMS patients.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127012

Traumatic Brain Injuries

A study undertaken in New York looked at HBOT in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. It confirmed the known benefits of HBOT for many aspects of brain injury and recovery including stroke, atherosclerosis, cerebral palsy, intracranial pressure, headache and brain and spinal cord injury and recommended further investigation.

https://link.springer.com/article/10.1007/BF02849960

A randomized Trial in the USA concluded that HBOT can induce neuroplasticity and significant brain function improvements in mild TBI patients with prolonged Post-Concussion-Syndrome at late chronic stage, even years after injury. Also that it can be effective in treating PTSD symptoms or repairing radiation damage and may slow down or even reverse metabolic disorders associated with neurodegenerative diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829860/

Dementia & Cognitive impairment

An article in Medical Gas Research reported on a 58-year-old female diagnosed with Alzheimer's dementia which had progressed rapidly over 8 months and for which there has been no effective treatment. An 8-week course of HBOT reversed the patient's symptomatic decline and continued HBOT in conjunction with medication maintained this improvement in symptoms and function over the next 22 months.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352566/

Mind & Memory

A New York study published in Aging Journal showed that HBOT induced cognitive enhancements in healthy aging adults via mechanisms involving regional changes in Cerebral blood flow. The main improvements include attention, information processing speed and executive functions, which normally decline with aging.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377835/

Autism

A study by the Medical University of Poznan, Poland said that research indicates the presence of cerebral hypoperfusion (decreased blood flow) in children with autism spectrum disorders (ASD). It stated that HBOT is one of the modern therapeutic methods that can counteract cerebral hypoperfusion in autistic children and the result of the study was that HBOT showed statistically significant improvements.

https://pubmed.ncbi.nlm.nih.gov/32218399/

Stroke

A study published for Brain Circulation suggested that HBOT provides a possible treatment for inflammation associated with many cerebrovascular diseases, limiting the damage done by them. HBOT can be an alternative method to other treatments for TBI and stroke such as invasive procedures and cell transplants.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785945/

An Israeli randomised trial concluded that HBOT can lead to significant neurological improvements in post stroke patients, even at chronic late stages. The observed clinical improvements imply that neuroplasticity can still be activated long after damage onset in regions where there is a brain anatomy/physiology mismatch. The patients who received Two months of 40 sessions (5 days/week), 90 minutes each showed significant improvement.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053716

Parkinson's Disease

A Japanese study published in Neuroscience Research used mice with induced Parkinson's and concluded that HBOT is effective in preventing the progression of Parkinson's disease. The therapy halted the decrease in dopaminergic neurons. These are the main source of dopamine in the central nervous system and their loss is associated with Parkinson's disease.

https://www.sciencedirect.com/science/article/pii/S0168010217304832

Anti-aging

In November 2020, in a huge breakthrough in anti-ageing, scientists at Tel Aviv University announced that they had successfully reversed the biological ageing process in a group of adults over 64 years old, using HBOT. Two important indicators of biological ageing are the shortening of telomeres - the ends of our DNA - and an increase in old, malfunctioning cells. In this study, both of these were significantly reversed, a result that no drug or other therapy has yet been able to achieve. In cellular terms, participants' bodies were taken back a massive 25 years. Treatment consisted of daily HBOT sessions for five days a week over three months - around 60 sessions in all.

https://neurosciencenews.com/aging-reverse-hyperbaric-oxygen-17295/